BDBM254547 US10214477, Example 6::US9469597, 6::US9670136, 6 N1-((trans)-2-(thiazol-5-yl)cyclopropyl)cyclohexane-1,4-diamine

SMILES NC1CCC(CC1)N[C@H]1C[C@@H]1c1cncs1

InChI Key InChIKey=LMSFGWYBIGVSHX-TVUZUIDESA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 254547   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254547(US10214477, Example 6 | US9469597, 6 | US9670136, ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:In order to monitor MAO enzymatic activities and/or their inhibition rate by inhibitor(s) of interest, a fluorescence-based (inhibitor)-screening ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254547(US10214477, Example 6 | US9469597, 6 | US9670136, ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254547(US10214477, Example 6 | US9469597, 6 | US9670136, ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Briefly, a fixed amount of MAO (0.25 μg for MAO-A and 0.5 μg for MAO-B) was incubated on ice for 15 minutes in the reaction buffer, in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent